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Product Description
anti- Cdc20 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome(APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation..
Immunogen: cell division cycle 20 homolog
Synonyms: CDC20, CDC20A, p55CDC
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab09997(CDC20 antibody) at dilution of 1:100
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09997(CDC20 antibody) at dilution of 1:1000
Gene ID: 991
Research Area: Metabolism
Uniprot ID: Q12834
