anti- CDC42 antibody

Product Description

anti- CDC42 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20..

Immunogen: cell division cycle 42 (GTP binding protein, 25kDa)

Synonyms: CDC42Hs;G25K;TKS

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab01530(CDC42 antibody) at dilution of 1:50

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01530(CDC42 antibody) at dilution of 1:1000

Gene ID: 998

Research Area: Metabolism

Uniprot ID: P60953