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Product Description
anti- CDK3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner..
Immunogen: cyclin-dependent kinase 3
Synonyms: CDKN3
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: Mouse brain were subjected to SDS PAGE followed by western blot with FNab01556(CDK3 antibody) at dilution of 1:2000
Gene ID: 1018
Research Area: Metabolism
Uniprot ID: Q00526
