anti- CEP290 antibody

Product Description

anti- CEP290 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290’s function is critical for IFT—in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining..

Immunogen: centrosomal protein 290kDa

Synonyms: BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP, IHC, IF

Recommended dilution: WB: 1:200-1:2000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human placenta using FNab01602(CEP290 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of ( -20? Ethanol ) fixed HeLa cells using FNab01602 ( CEP290 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab01602(CEP290 Antibody) at dilution of 1:600

Gene ID: 80184

Research Area: Metabolism

Uniprot ID: O15078