anti- CEP63 antibody

Product Description

anti- CEP63 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398)..

Immunogen: centrosomal protein 63kDa

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01606(CEP63 Antibody) at dilution of 1:50

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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab01606(CEP63 antibody) at dilution of 1:800

Gene ID: 80254

Research Area: Metabolism

Uniprot ID: Q96MT8