anti- CHAF1A antibody

Product Description

anti- CHAF1A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci(By similarity)..

Immunogen: chromatin assembly factor 1, subunit A(p150)

Synonyms: CAF, CAF1P150

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, WB, IP, IF

Recommended dilution: WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human cervix tissue slide using FNab01630(CHAF1A Antibody) at dilution of 1:50

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01630(CHAF1A antibody) at dilution of 1:2000

Gene ID: 10036

Research Area: Metabolism

Uniprot ID: Q13111