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Product Description
anti- Chk1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa..
Immunogen: CHK1 checkpoint homolog
Synonyms: CHEK1, Chk1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab01653(CHK1 Antibody) at dilution of 1:50
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab01653(CHK1 Antibody) at dilution of 1:1000
Gene ID: 1111
Research Area: Metabolism
Uniprot ID: O14757
