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Product Description
anti- CHOP; GADD153 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma..
Immunogen: DNA-damage-inducible transcript 3
Synonyms: C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP; GADD153, CHOP10, DDIT 3, DDIT3, GADD153
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000
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Image 4: Tunicamycin treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab01668(CHOP; GADD153 Antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: P35638
