anti- CHST14 antibody

Product Description

anti- CHST14 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development..

Immunogen: carbohydrate(N-acetylgalactosamine 4-0) sulfotransferase 14

Synonyms: D4ST1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human placenta using FNab01694(CHST14 antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01694(CHST14 antibody) at dilution of 1:600

Gene ID: 113189

Research Area: Metabolism

Uniprot ID: Q8NCH0