anti- CHTF18 antibody

Product Description

anti- CHTF18 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C(CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A(RPA) and by proliferating cell nuclear antigen(PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH..

Immunogen: CTF18, chromosome transmission fidelity factor 18 homolog(S. cerevisiae)

Synonyms: C16orf41, CTF18

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human cerebellum using FNab01701(CHTF18 antibody) at dilution of 1:100

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Image 4: Y79 cells were subjected to SDS PAGE followed by western blot with FNab01701(CHTF18 antibody) at dilution of 1:300

Gene ID: 63922

Research Area: Metabolism

Uniprot ID: Q8WVB6