anti- CITED2 antibody

Product Description

anti- CITED2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm(LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium(AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region..

Immunogen: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Synonyms: MRG1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab01721(CITED2 antibody) at dilution of 1:500

Gene ID: 10370

Research Area: Metabolism

Uniprot ID: Q99967