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Product Description
anti- CLSPN antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex(pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks..
Immunogen: claspin homolog(Xenopus laevis)
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IF, IP
Recommended dilution: WB: 1:200-1:1000; IP: 1:500-1:2000; IF: 1:20-1:200
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01775( Claspin antibody) at dilution of 1:300
Gene ID: 63967
Research Area: Metabolism
Uniprot ID: Q9HAW4
