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Product Description
anti- CNDP2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343)..
Immunogen: CNDP dipeptidase 2(metallopeptidase M20 family)
Synonyms: CN2, CPGL, HEL-S-13, PEPA
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab01795(CNDP2 antibody) at dilution of 1:200
Gene ID: 55748
Research Area: Metabolism
Uniprot ID: Q96KP4
