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Product Description
anti- Collagen Type IV antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and-9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins..
Immunogen: collagen, type IV, alpha 2
Synonyms: COL4A2, Collagen alpha 2(IV) chain, Collagen Type IV, collagen, type IV, alpha 2, DKFZp686I14213, FLJ22259
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recommended dilution: IHC: 1:20-1:200
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Image 4: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab01844(Collagen Type IV antibody) at dilution of 1:50
Gene ID: 1284
Research Area: Metabolism
Uniprot ID: P08572
