anti- COMT antibody

Product Description

anti- COMT antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters..

Immunogen: catechol-O-methyltransferase

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IF, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney using FNab01856(COMT antibody) at dilution of 1:100

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01856( COMT Antibody) at dilution of 1:1000

Gene ID: 1312

Research Area: Metabolism

Uniprot ID: P21964