anti- Connexin-43 antibody

Product Description

anti- Connexin-43 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity)..

Immunogen: gap junction protein, alpha 1, 43kDa

Synonyms: Connexin-43, CX43, DFNB38, Gap junction alpha 1 protein, GJA1, GJAL, ODDD

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, FC, IP

Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded mouse heart using FNab01861(GJA1 antibody) at dilution of 1:100

Image 2: Immunofluorescent analysis of ( -20? Ethanol ) fixed HeLa cells using FNab01861 at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L).

Image 3: IP Result of anti-Connexin-43 (IP: FNab01861, 4ug; Detection: FNab01861 1:1000) with mouse heart tissue lysate 3200ug.

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab01861(GJA1 antibody) at dilution of 1:1000

Gene ID:

Research Area: Metabolism

Uniprot ID: P17302