anti- COPS4 antibody

Product Description

anti- COPS4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively..

Immunogen: COP9 constitutive photomorphogenic homolog subunit 4(Arabidopsis)

Synonyms: CSN4

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab01872(COPS4 Antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: A2780 cells were subjected to SDS PAGE followed by western blot with FNab01872(COPS4 antibody) at dilution of 1:500

Gene ID: 51138

Research Area: Metabolism

Uniprot ID: Q9BT78