anti- CPEB1 antibody

Product Description

anti- CPEB1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element(CPE), an uridine-rich sequence element(consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation(By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses(By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation(By similarity). Induces the assembly of stress granules in the absence of stress..

Immunogen: cytoplasmic polyadenylation element binding protein 1

Synonyms: CPEB

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01917(CPEB1 Antibody) at dilution of 1:50

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Image 4: A375 cells were subjected to SDS PAGE followed by western blot with FNab01917(CPEB1 antibody) at dilution of 1:1000

Gene ID: 64506

Research Area: Metabolism

Uniprot ID: Q9BZB8