anti- CRK antibody

Product Description

anti- CRK antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described..

Immunogen: v-crk sarcoma virus CT10 oncogene homolog (avian)

Synonyms:

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab01981(CRK antibody) at dilution of 1:100

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab01981(CRK antibody) at dilution of 1:1000

Gene ID: 1398

Research Area: Metabolism

Uniprot ID: P46108