anti- CTSC antibody

Product Description

anti- CTSC antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis..

Immunogen: Cathepsin C

Synonyms: CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab09934 (CTSC antibody) at dilution of 1:100

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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab09934 (CTSC antibody) at dilution of 1:1000

Gene ID: 1075

Research Area: Metabolism

Uniprot ID: P53634