anti- CX3CL1 antibody

Product Description

anti- CX3CL1 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1(PubMed:23125415, PubMed:9931005, PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site(site 1) in integrins. In the absence of CX3CR1, binds to a second site(site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1(PubMed:23125415, PubMed:24789099). The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium(PubMed:9024663, PubMed:9177350)..

Immunogen: chemokine(C-X3-C motif) ligand 1

Synonyms: FKN, NTT, SCYD1

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab02089( CX3CL1 Antibody) at dilution of 1:200

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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab02089(CX3CL1 antibody) at dilution of 1:1000

Gene ID: 6376

Research Area: Metabolism

Uniprot ID: P78423