anti- Cytokeratin 1-specific antibody

Product Description

anti- Cytokeratin 1-specific antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I..

Immunogen: keratin 1

Synonyms: 67 kDa cytokeratin, CK 1, CK1, Cytokeratin 1, keratin 1, KRT1

Reactivity: Human, Mouse

Tested Application: ELISA, IP, IF, WB, IHC

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab02211(KRT1-specific antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of A431 cells using FNab02211 ( KRT1-specific Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Image 3: IP Result of anti-KRT1-specific (IP: FNab02211, 3ug; Detection: FNab02211 1:500) with A431 cells lysate 3500ug.

Image 4: mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab02211(KRT1-specific Antibody) at dilution of 1:1000

Gene ID:

Research Area: Metabolism

Uniprot ID: P04264