anti- DACH1 antibody

Product Description

anti- DACH1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter(By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain(By similarity)..

Immunogen: dachshund homolog 1(Drosophila)

Synonyms: DACH

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IP, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human oesophagus cancer tissue slide using FNab02230(DACH1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Image 2: .

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02230(DACH1 Antibody) at dilution of 1:600

Gene ID: 1602

Research Area: Metabolism

Uniprot ID: Q9UI36