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Product Description
anti- DIS3L2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem(ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation..
Immunogen: DIS3 mitotic control homolog(S. cerevisiae)-like 2
Synonyms: FAM6A
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02396( DIS3L2 Antibody) at dilution of 1:600
Gene ID: 129563
Research Area: Metabolism
Uniprot ID: Q8IYB7
