anti- DKK1 antibody

Product Description

anti- DKK1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease..

Immunogen: dickkopf homolog 1

Synonyms: Dickkopf 1, Dickkopf related protein 1, DKK 1, DKK1, hDkk 1, SK

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC

Recommended dilution: WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human gliomas tissue slide using FNab02401(DKK1 Antibody) at dilution of 1:200

Image 2: Immunofluorescent analysis of HepG2 cells, using DKK1 antibody FNab02401 at 1:25 dilution.

Image 3:

Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab02401(DKK1 antibody) at dilution of 1:500

Gene ID: 22943

Research Area: Metabolism

Uniprot ID: O94907