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Product Description
anti- DKK2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease(By similarity)..
Immunogen: dickkopf homolog 2
Synonyms: Dickkopf 2, Dickkopf related protein 2, DKK 2, DKK2, hDkk 2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human cervix using FNab02402(DKK2 antibody) at dilution of 1:50
Image 2: .
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Image 4: mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab02402(DKK2 antibody) at dilution of 1:500
Gene ID: 27123
Research Area: Metabolism
Uniprot ID: Q9UBU2
