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Product Description
anti- DMAP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described..
Immunogen: DNA methyltransferase 1 associated protein 1
Synonyms: KIAA1425
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab02421(DMAP1 antibody) at dilution of 1:100
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02421(DMAP1 antibody) at dilution of 1:1000
Gene ID: 55929
Research Area: Metabolism
Uniprot ID: Q9NPF5
