Euro
British Pound
US Dollar
Product Description
anti- DNMT3A antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3(H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity..
Immunogen: DNA(cytosine-5-)-methyltransferase 3 alpha
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution:
Image 1:
Image 2: .
Image 3:
Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02485(DNMT3A antibody) at dilution of 1:1500
Gene ID: 1788
Research Area: Metabolism
Uniprot ID: Q9Y6K1
