anti- DOCK7 antibody

Product Description

anti- DOCK7 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms..

Immunogen: dedicator of cytokinesis 7

Synonyms: dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution: WB: 1:200-1:1000; IP: 1:500-1:1000

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Image 3: IP Result of anti-DOCK7 (IP: FNab02497, 3ug; Detection: FNab02497 1:500) with mouse brain tissue lysate 8000ug.

Image 4: mosue brain tissue were subjected to SDS PAGE followed by western blot with FNab02497(DOCK7 antibody) at dilution of 1:400

Gene ID: 85440

Research Area: Metabolism

Uniprot ID: Q96N67