anti- EBI3 antibody

Product Description

anti- EBI3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro-and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells(TH1), type 2 effector cells(TH2) and IL17 producing helper T-cells(TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines..

Immunogen: Epstein-Barr virus induced 3

Synonyms: IL27B

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02615(EBI3 antibody) at dilution of 1:300

Gene ID: 10148

Research Area: Metabolism

Uniprot ID: Q14213