anti- ECD antibody

Product Description

anti- ECD antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP(PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes(PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins(PubMed:19640839). The cell cycle-regulating function may depend on its RUVBL1-mediated association with the R2TP complex(PubMed:26711270). May play a role in regulation of pre-mRNA splicing(PubMed:24722212)..

Immunogen: ecdysoneless homolog(Drosophila)

Synonyms:

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IF, IP

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02619(ECD antibody) at dilution of 1:300

Gene ID: 11319

Research Area: Metabolism

Uniprot ID: O95905