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Product Description
anti- EED antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Polycomb group(PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A..
Immunogen: embryonic ectoderm development
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab02640(EED antibody) at dilution of 1:1000
Gene ID: 8726
Research Area: Metabolism
Uniprot ID: O75530
