anti- EIF3M antibody

Product Description

anti- EIF3M antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2)..

Immunogen: eukaryotic translation initiation factor 3, subunit M

Synonyms: HFLB5, PCID1

Reactivity: Human

Tested Application: ELISA, WB, IF

Recommended dilution: WB: 1:500-1:2000; IF: 1:10-1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02715(EIF3M antibody) at dilution of 1:1000

Gene ID: 10480

Research Area: Metabolism

Uniprot ID: Q7L2H7