anti- ELL2 antibody

Product Description

anti- ELL2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain(IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression..

Immunogen: elongation factor, RNA polymerase II, 2

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02741(ELL2 antibody) at dilution of 1:1000

Gene ID: 22936

Research Area: Metabolism

Uniprot ID: O00472