anti- EPHB4 antibody

Product Description

anti- EPHB4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis..

Immunogen: EPH receptor B4

Synonyms: EPH receptor B4, EPHB4, Ephrin type B receptor 4, HTK, MYK1, TYRO11, Tyrosine protein kinase TYRO11

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, FC, WB

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas tissue using FNab02807(EPHB4 antibody) at dilution of 1:50

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02807(EPHB4 Antibody) at dilution of 1:1000

Gene ID: 2050

Research Area: Metabolism

Uniprot ID: P54760