anti- EPRS antibody

Product Description

anti- EPRS antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT(gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs(such as ceruplasmin) and suppresses their translation..

Immunogen: glutamyl-prolyl-tRNA synthetase

Synonyms: GLNS, PARS, QARS, QPRS

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02817( EPRS Antibody) at dilution of 1:600

Gene ID: 2058

Research Area: Metabolism

Uniprot ID: P07814