anti- ER antibody

Product Description

anti- ER antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined..

Immunogen: estrogen receptor 1

Synonyms: DKFZp686N23123, ER, ER alpha, Era, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue using FNab02822(ESR1 antibody) at dilution of 1:100

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Image 4: hela cells were subjected to SDS PAGE followed by western blot with FNab02822( ER Antibody) at dilution of 1:1000

Gene ID: 2099

Research Area: Metabolism

Uniprot ID: P03372