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Product Description
anti- ERAB antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD)..
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
Synonyms: 17 beta HSD 10, 17b HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD17B10, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, Type II HADH, XH98G2
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution: WB: 1:1000-1:4000
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02824(ERAB Antibody) at dilution of 1:2000
Research Area: Metabolism
Uniprot ID: Q99714
