anti- ERBB4 antibody

Product Description

anti- ERBB4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized..

Immunogen: v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Synonyms: HER4

Reactivity: Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded rat lung using FNab02829(ERBB4 antibody) at dilution of 1:100

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02829(ERBB4 antibody) at dilution of 1:1000

Gene ID: 2066

Research Area: Metabolism

Uniprot ID: Q15303