anti- ERCC1 antibody

Product Description

anti- ERCC1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links(ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair(HDR) of DNA double-strand breaks, in conjunction with SLX4..

Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 1(includes overlapping antisense sequence)

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab02832(ERCC1 antibody) at dilution of 1:50

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02832(ERCC1 antibody) at dilution of 1:300

Gene ID: 2067

Research Area: Metabolism

Uniprot ID: P07992