anti- EXD1 antibody

Product Description

anti- EXD1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity)..

Immunogen: exonuclease 3'-5' domain containing 1

Synonyms: EXDL1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab02889( EXD1 antibody) at dilution of 1:200

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02889( EXD1 Antibody) at dilution of 1:300

Gene ID: 161829

Research Area: Metabolism

Uniprot ID: Q8NHP7