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Product Description
anti- EZH1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Polycomb group(PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di-and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation..
Immunogen: enhancer of zeste homolog 1(Drosophila)
Synonyms: KIAA0388
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab02917(EZH1 antibody) at dilution of 1:1000
Gene ID: 2145
Research Area: Metabolism
Uniprot ID: Q92800
