anti- FAM20C antibody

Product Description

anti- FAM20C antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039)..

Immunogen: family with sequence similarity 20, member C

Synonyms: Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:1000-1:10000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab02979(FAM20C Antibody) at dilution of 1:50

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Image 4: mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab02979(FAM20C Antibody) at dilution of 1:1000

Gene ID: 56975

Research Area: Metabolism

Uniprot ID: Q8IXL6