anti- FBP1 antibody

Product Description

anti- FBP1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain..

Immunogen: fructose-1,6-bisphosphatase 1

Synonyms: FBP, FBP1, FBPase 1, fructose 1,6 bisphosphatase 1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IF, IP

Recommended dilution: WB: 1:5000-1:20000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab03029( FBP1 Antibody) at dilution of 1:200

Image 2: Immunofluorescent analysis of HeLa cells using FNab03029 (FBP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3: IP Result of anti-FBP1 (IP: FNab03029, 4ug; Detection: FNab03029 1:500) with HepG2 cells lysate 3200ug.

Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03029(FBP1 antibody) at dilution of 1:5000

Gene ID: 2203

Research Area: Metabolism

Uniprot ID: P09467