anti- Fibrinogen beta chain antibody

Product Description

anti- Fibrinogen beta chain antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene..

Immunogen: fibrinogen beta chain

Synonyms: FGB, fibrinogen beta chain

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab03117(FGB antibody) at dilution of 1:50

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Image 4: mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab03117(FGB antibody) at dilution of 1:1000

Gene ID: 2244

Research Area: Metabolism

Uniprot ID: P02675