anti- FKBP1A antibody

Product Description

anti- FKBP1A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed..

Immunogen: FK506 binding protein 1A, 12kDa

Synonyms: FKBP1, FKBP12

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor using FNab03136(FKBP1A antibody) at dilution of 1:100

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03136( FKBP1A Antibody) at dilution of 1:1000

Gene ID: 2280

Research Area: Metabolism

Uniprot ID: P62942