anti- GLRA1 antibody

Product Description

anti- GLRA1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Glycine receptors are ligand-gated chloride channels(PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine(PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization(PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability(PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Channel activity is potentiated by ethanol(PubMed:25973519). Potentiation of channel activity by intoxicating levels ot ethanol contribute to the sedative effects of ethanol(By similarity)..

Immunogen: glycine receptor, alpha 1

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03486(GLRA1 antibody) at dilution of 1:500

Gene ID: 2741

Research Area: Metabolism

Uniprot ID: P23415