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Product Description
anti- GLRB antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1(PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability(PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488)..
Immunogen: glycine receptor, beta
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03489( GLRB Antibody) at dilution of 1:1000
Gene ID: 2743
Research Area: Metabolism
Uniprot ID: P48167
