Product Description
anti- GOT1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain..
Immunogen: glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
Synonyms: AATC, CAT, GIG18, GOT1, Transaminase A
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, IF, WB
Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab09876(GOT1 antibody) at dilution of 1:100
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09876(GOT1 antibody) at dilution of 1:1000
Gene ID: 2805
Research Area: Metabolism
Uniprot ID: P17174