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Product Description
anti- GRK6 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis(By similarity). Phosphorylates rhodopsin(RHO)(in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling(in vitro)..
Immunogen: G protein-coupled receptor kinase 6
Synonyms: GPRK6
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03656(GRK6 antibody) at dilution of 1:1000
Gene ID: 2870
Research Area: Metabolism
Uniprot ID: P43250
